How To Write A Letter Of Resignation Nurse . Due to a recent diagnosis, i have become aware that my illness will require extended treatment and. If you are a qualified nurse who has found a new role and you are looking to resign from your current position, then you need to write a detailed resignation letter stating that you are resigning from your current role. FREE 13+ Nurse Resignation Letter Samples and Templates in PDF MS Word from www.sampletemplates.com Depending on the support staff, the nurse should try and give as much time as needed for the medical office or hospital to adjust to the loss. Other elements that can be in your resignation letter though not essential are; Letters of resignation are often a formality and they can typically be short and to the point.